Posted by Michael Bell on February 16, 2006, at 22:18:50
In reply to What's Different Between the Old and New Nardil?, posted by shasling on January 26, 2006, at 10:05:59
Hey folks, long time no see. Sometimes I peruse this board quickly to see what the topics are, and so I decided to respond to this one since it is an issue I have dealt with to a huge exent.
From the descriptions of others, research and my own experiences, I believe there are two problems with the new nardil as compared to the old:
1) new nardil is absorbed before it reaches the new intestine
2) even if new nardil does reach the new intestine, the absorbtion *rate* is off balance
That's why placing nardil in plasmin plus enteric tabs were only partially effective. yes, more phenelzine would likely survive the trip through the stomach, but once the enteric tab dissolved, the nardil itself won't be absorbed to the maximum level without an excipient to aid it.
The best excipients to aid absorption into the small intestine are sugar invert (a.k.a. honey) and ethanol (alcohol). Sugar is quite good, but the absorbtion rate, though high, is relatively slow.
As far as absorption into the small intestine, NOTHING beats alcohol. It's rate and level of absorption by the small intestine is extremely high. Obviously, I don't mean kick back shots of tequila, I'm talking mere drops of the substance.
Therefore mixing nardil with either honey or alcohol has been much more effective.
poster:Michael Bell
thread:602979
URL: http://www.dr-bob.org/babble/20060212/msgs/610471.html