Posted by SLS on January 28, 2006, at 6:35:18
In reply to Re: Mifepristone failure? Maybe not. » SLS, posted by Sarah T. on January 27, 2006, at 21:46:45
> Just last night, I was wondering where you were. I imagined you basking in the sun somewhere in the Caribbean.
Then, we were imagining the same thing!
> Were you participating in a study of RU486?No. I was taking it on an open-label basis through a compassionate use program.
> Is that how you were able to obtain it?
I obtained it through the Feminist Majority Foundation once my use of it was approved by the FDA. You can start the process by calling the Feminist Majority Foundation at:
Julianna Zuccaro
703-522-2214
You will also need two forms available on the FDA website. They are #1571 and #1572 applications for IND.http://www.fda.gov/cder/regulatory/applications/Forms.htm
> My urinary cortisol levels have been so high for years, regardless of whether I've been on meds or not. I would like to try Mifepristone.
So far, mifepristone has been used primarily to treat psychotic depression and bipolar depression, ailments known to display high cortisol levels.
http://www.clinicaltrials.gov/show/NCT00043654
> I'm sorry to hear you've been feeling so washed out.
This feeling has been slowly dissipating now that I have discontinued the mifepristone.
> Do you think that might be a function of the dose?
To some degree. Dosages of 50-1200mg were used in the early studies in order to find an optimal effective dosage.
> Must you take the same dose next time? How did they come up with that dose?
600mg is what has been chosen by the FDA to use in their compassionate use protocol. It seems to be a more than adequate dosage.
I am very disappointed that I am not feeling any improvement at all right now.
- Scott
poster:SLS
thread:603490
URL: http://www.dr-bob.org/babble/20060122/msgs/603693.html