Posted by shasling on January 25, 2006, at 7:05:37
In reply to Re: Tired-all the time? advice?, posted by jedi on January 25, 2006, at 3:02:49
Thank you Jedi. Thank you thank you thank you. Where have you been all my life? : ) Wow, what an 'oh yeah' moment this was! Something big just finally clicked into place...
I ALWAYS knew there was a gluccocorticoid deficiency. Since antidepressants never helped, I can't tell you how many years I've been reading books about adrenal fatigue, chronic fatigue, HPA axis, ACTH, dexamethasone, etc and found they were all written about me. But try getting a doc to test your HPA feedback loop; they hate when you know more than they do, so immediately just assume hypochondriasis and discount the suggestion. Then, by mistake, the only time I ever felt GOOD, ever, was when treated for an infection or somethign with 40 mg p/day of cortisol. Years later I finally got a doc to prescribe a smaller daily amount and it felt okay for a while, not as good as the 40 mg, but you know, better. However, the benefit has been lost now. So I now suspected not just a low cortisol level but a feedback thing of some kind.
Just in the past few weeks found the atypical depression diagnosis and knew it was me immediately, and read everything I could on it, but missed the one you posted. I'm on Parnate which kinda works then doesn't then works then doesn't. Feels like I'm kinda chasing the dragon with it. And to be truthful, it feels more like the amphetamine metabolites (to which I'm just super super sensitive) that I feel. I can take one and feel it within an hour and I'm not sure the actual AD effects of Parnate are supposed to work that way.
Do you know if the HPA regulation effects are limited to Nardil? And not Parnate? Kinda what it sounds like, but Nardil may just be the one they chose for the study... Just wondering if you have other knowledge of that.
I'd take it to my pdoc, but you know he'd never take the two minutes to read it. But you have given me hope for something after the Parnate cause I'm starting to worry about it. How very sad that atyp depr is commonly mistaken for chronic fatigue and the like by docs who have just not heard of it. What a colossal waste of lives.
Anyway, Jedi, thanks for knowing about it and posting that. You have made my morning. I feel like I've just now seen land after being at sea for 30 years. I love this place.
Hopeful again,
Suzie
poster:shasling
thread:600569
URL: http://www.dr-bob.org/babble/20060122/msgs/602580.html