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Re: Keppra for benzo taper and/or mood stabilizer... ? » cache-monkey

Posted by ed_uk on January 19, 2006, at 14:25:35

In reply to Re: Keppra for benzo taper and/or mood stabilizer... ? » ed_uk, posted by cache-monkey on January 18, 2006, at 19:39:41

Hi CM

>Do you have a reason for suggesting Librium instead of the traditional Valium?

I thought your doc might be more comfortable with it. Valium seems to have aquired a particularly bad reputation in the US. Silly really.

>They seem to have the same long-acting metabolite, based on what I can tell from Ashton's manual. But the half life of Valium itself seems to be longer than Librium. I'm wondering if this might cause a difference in reaction to tapering...

I think you'd find them similarly effective for tapering. Valium is the 'traditional' drug for doing benzo tapers in the UK, but probably not in the US. Librium is the 'traditional' drug for treating alcohol withdrawal symptoms, probably because of its (apparantly) lower 'street value'.

>I've seen references (from Scott and others) to "anti-kindling" properties of Keppra. Do you know anything about this?

Keppra is very 'experimental' in psychiatry. There's no good evidence that it's actually effective in treating any psychiatric disorder. It's only really established as an antiepileptic. I'm not saying that it doesn't work, just that it's unproven.

Regards

Ed


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