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Re: Depressed/agitated/wired - soft bipolar? » ed_uk

Posted by 4WD on January 17, 2006, at 22:40:10

In reply to Re: Depressed/agitated/wired - soft bipolar? » 4WD, posted by ed_uk on January 17, 2006, at 16:11:39

> Hi Marsha
>
> I'd be tempted to return to imipramine. You can take as little as 5mg at first and increase gradually. The 10mg tablets are useful for titration.
>
> >And I guess I could take some drug for the inevitable horrible dry mouth.
>
> Yes, there are a couple of meds which might help.
>
> Ed


Ed,

When I was on imipramine in 1986-87, I was taking 50mg t.i.d. And doing well (except for pretty bad side effects). Is it possible that such a low dose would help without such bad SEs?

Do you know why SSRIs are so much more likely to cause anxiety than TCAs? This seems to be the significant issue here.

I thought serotonin was supposed to the "calming" neurotransmitter. Of course, dopaminergic drugs make me nervous and so so noradrenergic ones.

Go figure.

Marsha


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