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Re: can Parnate increase GABA like Nardil does?

Posted by chess on January 11, 2006, at 23:04:25

In reply to Re: can Parnate increase GABA like Nardil does?, posted by djmmm on January 11, 2006, at 21:56:44

GABA(B) is the sedative receptor
GABA(A) is the anxiolytic receptor
right?
that's why drugs they're working on (like ocinaplon) only affect GABA(A) receptors
benzos affect GABA A + B receptors

> > i know that Nardil elevates the level of GABA in the brain, but can Parnate also elevate the level of GABA too?
> >
> >
>
> Parnate increases GABA(B) receptor activity in the cerebral cortex. (Effects of stress and tranylcypromine on amphetamine-induced locomotor activity and GABA(B) receptor function in rat brain.
> )


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poster:chess thread:598083
URL: http://www.dr-bob.org/babble/20060108/msgs/598190.html