Posted by linkadge on December 28, 2005, at 12:14:35
In reply to Re: what is Fos-Immunoreactivity? » linkadge, posted by Larry Hoover on December 28, 2005, at 10:33:28
I would be interested in the effect that lithium or antipsychotics could have on the effects of c-fos induced by antidepressants. So lithium has an attenuating effect on c-fos in certain situations. Is this of relavance to its mood stabalizing effect?
So parnate and bupropion seemed to consistantly increase c-fos in more areas of the brain than other antidepressants. Is this related to the propensity for these two drugs to resemble psychostimulants in certain paradigms? Would the addition of lithium or an antipsychotic reduce certain activation, would it preserve c-fos acivation in the amygdala?
I wonder if deltaFosB is affected by parnate or bupropion. A member of the fos family that generally takes longer to turn on, has been linked to certain substance's addictivness.
Linkadge
poster:linkadge
thread:590496
URL: http://www.dr-bob.org/babble/20051221/msgs/592751.html