Posted by SLS on December 12, 2005, at 7:02:58
In reply to Re: Valdoxan (agomelatine) - Any news? » Rayray, posted by lunesta on December 12, 2005, at 6:06:29
Hi.
> My question is how is this different than the currently available sleep medicine Rozerem, also a high affinity MT1 and MT2 melatonergic agonist.
>
> They have the exact same profile. Different drugs, different purpose, nearly the same exact binding sites.Agomelatine does other things as well. For instance, it is a competitive antagonist at the 5-HT2C receptor. Small differences in drugs can have profound effects.
> I would bet Rozerem can and would work as an antidepressant as well. I am asking my doc for it for sleep.I wish you luck. Please post your experiences with Rozerem. If it works for you as an antidepressant, I would like to put it on my list of things to try. Unfortunately, taking melatonin seems to make me feel worse.
- Scott
poster:SLS
thread:588199
URL: http://www.dr-bob.org/babble/20051211/msgs/588287.html