Posted by Emme on December 11, 2005, at 11:21:50
In reply to Re: Be wary of benzos affecting effacy of other me, posted by JohnKeats on December 10, 2005, at 1:30:01
>….. So my reasoning was that the clonazepam was impairing the effacy of Elavil, and possibly the other AD drugs I had tried. This has nothing to do with the effects of clonazepam on anxious symptoms.
When you said that you thought it was impairing the efficacy of other meds, I read this to mean that you believed that there is a pharmacologic interaction between the meds whereby the benzodiazepine was altering the metabolism of the other drugs (perhaps that’s not what you meant). My point was that that doesn’t necessarily follow from your experience. It may simply be that the effects of the clonazepam were offsetting the benefits of the other drugs for you, but not necessarily increasing or decreasing their clearance per se. I’d have to look a little further to learn about any pharmacologic interactions. And someone here probably already knows that. But as I said, perhaps you were not thinking in terms of actual interactions.
> I'm not advocating the banishment of benzos.
That’s good.
> The post didn't say throw out the benzo, it said try stopping it briefly for one or two days
I would agree that it may not hurt to see how what happens if you drop it down temporarily. I think that would apply in many situations where you aren’t sure if one of the meds is helping or needed; lower it and see how it goes.
>. That's my own experience and reaction with drugs, like with everything else on PB I thought the YMMV was evident.
The YMMV was not evident to me. Your statements came across to me as generalizations that for many people don’t apply. Benzos do work well long term and at stable dosages for lots of people (myself included).
emme
poster:Emme
thread:586809
URL: http://www.dr-bob.org/babble/20051211/msgs/588029.html