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Re: Generally what is the most effective SSRI?

Posted by blueberry on December 6, 2005, at 4:47:22

In reply to Generally what is the most effective SSRI?, posted by rjlockhart on December 5, 2005, at 21:00:02

Yeah, I agree with everyone here that only trial and error will identify which one is best for you.

They all do basically the same thing, but they are completely different molecules, and they all do significantly different things than just serotonin. One med might have high affinity for one person's receptors while it might have lower affinity for someone else's, probably having a lot to do with genetics at the molecular level. Just my guess.

Zoloft can touch dopamine, hardly at all in some people but bigtime in other people. Same with paxil except with norepinephrine. Luvox has some action on dopamine, most specifically when combined with seroquel.

They are all very different, not interchangeable, amd will have dramatically different results from one person to the next.
Just my opinions though.


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URL: http://www.dr-bob.org/babble/20051203/msgs/586002.html