Re: very interesting » pseudoname

Posted by zeugma on October 31, 2005, at 22:48:34

In reply to very interesting » zeugma, posted by pseudoname on October 29, 2005, at 11:02:53

hi pseudoname, this is the Strattera opioid reference:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15225731
Bioorg Med Chem Lett. 2004 Aug 2;14(15):4083-5. Related Articles, Links

Synthesis and biological evaluation of the major metabolite of atomoxetine: elucidation of a partial kappa-opioid agonist effect.
Creighton CJ, Ramabadran K, Ciccone PE, Liu J, Orsini MJ, Reitz AB.
Drug Discovery, Johnson and Johnson Pharmaceutical, Research and Development, Spring House, PA 19477-0776, USA. ccreight@prdus.jnj.com
The major human metabolite of atomoxetine (4-hydroxyatomoxetine) was tested against a panel of receptors and enzymes, and was found to interact with the mu, delta, and kappa-opioid receptors based upon studies involving both binding and functional assays. 4-hydroxyatomoxetine was determined to be a partial agonist of the kappa-opioid receptor.>>
-z

Thread

good events feel BAD pseudoname 10/26/05
Re: good events feel BAD lunesta 10/26/05
Re: Yes, that makes sense UgottaHaveHope 10/27/05
Re: Yes, that makes sense » UgottaHaveHope pseudoname 10/27/05
Since you mention psychoanalysis » pseudoname Declan 10/28/05
Re: Since you mention psychoanalysis » Declan pseudoname 10/28/05
ADHD? zeugma 10/29/05
very interesting » zeugma pseudoname 10/29/05
Re: ADHD? alohashirt 10/31/05
Re: very interesting » pseudoname zeugma 10/31/05
Strattera and kappa receptors » zeugma pseudoname 11/1/05
Dextroamphetamine, or? » pseudoname Paulbwell 11/3/05
Re: Dextroamphetamine, or? » Paulbwell pseudoname 11/3/05

Post a new follow-up

Notify the administrators

Start a new thread

poster:zeugma thread:572130
URL: http://www.dr-bob.org/babble/20051031/msgs/573972.html

	for
in