Posted by SLS on October 31, 2005, at 1:46:56
In reply to Re: lithium- initial effect then apathy, posted by Phillipa on October 30, 2005, at 20:33:21
> Nortriptalline put me to sleep and I couldn't wakeup the next day till two pm. I felt like I was part of the bed. Fondly, Phillipa
Nortriptyline affected me the same way the first time I tried it. It took a few days for the somnolence to disappear, as it appears this was a startup side effect. If you never gave nortriptyline more than a day or two, I would consider retaining it on your list of things to try.
Most people respond best to 75mg. However, nortriptyline is the best-studied antidepressant drug for blood-levels versus response, so it is easier to determine dosages. I take 100mg. If you take too much, you can actually lose the antidepressant response, so dosage determination is more critical with nortriptyline than it is for the other TCAs. As a guideline, blood levels should range between 50-150 ng/ml. Of course, some people will need to be higher and some people lower. Clinical titration is still necessary.
Of course, there are other TCAs.
- Scott
poster:SLS
thread:573495
URL: http://www.dr-bob.org/babble/20051024/msgs/573653.html