Posted by ravenstorm on October 27, 2005, at 17:39:03
In reply to Re: Valdoxan--caution about no withdrawal » ravenstorm, posted by jrbecker on October 27, 2005, at 16:36:25
Really, its in phase III trials in the U.S.????? I didn't know that. I may have to contact the company and see if they are still accepting guinea pigs!!
Wow, two hours?? It must have longer acting metabolites then? I don't see how the drug could last all day in your system with two hour half life. And you couldn't dose multiple times a day with this drug because of the sedation from the melatonin acting part of the drug. I must have this drug totally confused with another. For some reason I thought it had a 70 hour half life. My bad. My apologies everybody.
As far as remeron, serzone etc not having as bad as withdrawal. I had bad withdrawal to remeron as well as paxil. I think it was you who posted a while back a warning from the UK that up to 15% of people can experience significant withdrawal to remeron lasting anywhere from a week or two to a few months. I brought that right into my pdoc to prove I hadn't just been "imagining" my symptoms!
The people in these studies must not be as med sensitive as me. The study you quoted (and seriously, THANK YOU for all the cutting edge information you post) states that in the second week there was no difference in discontinuation syndromes between the two groups. I for one had severe paxil withdrawal symptoms for way more than two weeks!! Wellbutrin and prozac are the only drugs I haven't had withdrawal from!
Anyway, I would still love to try this drug, withdrawal syndrome or not.
Again, thanks so much for all your posts. If you happen to have time to explain the two hour thing to me (how it can last all day) that would be great.
poster:ravenstorm
thread:571357
URL: http://www.dr-bob.org/babble/20051024/msgs/572469.html