Posted by med_empowered on October 26, 2005, at 15:18:49
In reply to Re: Tapered down from 20 mg Zyprexa » DanielJ, posted by Sebastian on October 26, 2005, at 10:40:48
Instead of doing combos with atypicals..maybe an old-school ap (at a low-dose, of course) would be a good idea? There was a recent study that found Trilafon (perphenazine) compared very well to zyprexa...I think zyprexa had a **slight** edge, but it was pretty minor. If you keep the AP dose low, you could get necessary antipsychotic action w/ minimal side effects (the EPS seen with old drugs might be b/c they used to be given in such high doses). Plus, perphenazine is pretty good for mania and depression (that's why it was put in Triavil, for agitated depression and depression in schizophrenia). So..maybe something like perphenazine, or loxapine, at low-doses, maybe with buspirone added and maybe an anti-depressant would be good? It seems like you could avoid weight gain that way, and probably also avoid EPS.
poster:med_empowered
thread:571717
URL: http://www.dr-bob.org/babble/20051024/msgs/572141.html