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Re: Provigil for ADHD question

Posted by med_empowered on October 18, 2005, at 4:04:36

In reply to Re: Provigil for ADHD question, posted by rjlockhart98 on October 17, 2005, at 22:33:05

I think I saw a couple studies (nothing exciting--small samples, not well randomized...just "for the hell of it" psychiatric experiments, I guess) where Provigil was co-administered with amphetamine. The one I can remember used very low-dose dexedrine (20mgs) along with full-dose Provigil, after the subjects had been taking full-dose Provigil for about a week. The study focused on side-effects, and it was pretty good--neither arm (provigil, or provigil+amphetamine) differed all that much from placebo in terms of side effects. Given Provigil's profile--low effects on locomotion, little effect on sleep quanitity or quality, very *mild* weight-reducing properties, low propensity to cause cardiovascular issues-- my guess would be that you'll see a synergistic combination; both meds working better, and at lower doses.


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