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Attenace and Nuvigil - any point?

Posted by tecknohed on October 16, 2005, at 8:41:59

I've read that these 2 drugs are in the pipeline for ADHD. Yet they 'are' both modafinil, which of course is already in use.

Attenace is basically just modafinil (Provigil) in specific/higher doses. Uh, why?

"The Attenace application is one way Cephalon is trying to protect its Provigil revenues, said Ilya Kravets, an analyst with investment research firm Mehta Partners of New York. Because Attenace is a different dose of modafinil than Provigil, the FDA treats it as a different drug and it can receive its own patent protections."
http://www.modafinil.com/article/attenace.html
Says it all really!

As for Nuvigil, a single isomer of modafinil, it seems to me to be just another Lexapro 'wannabe'.
It is said to last longer in the body than Provigil and may have less of an interaction with birth control pills, which Provigil can render less effective. These would clearly be worthwhile changes but how exactly would removing the inactive isomer bring about such a change in action? Anybody?

Teck.


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poster:tecknohed thread:567533
URL: http://www.dr-bob.org/babble/20051010/msgs/567533.html