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naltrexone theory » Declan

Posted by pseudoname on October 2, 2005, at 10:11:58

In reply to Re: naltrexone » pseudoname, posted by Declan on October 1, 2005, at 19:51:33

> ...whereas you're getting relief from an antagonist

It's actually too early to say that but, yes, that's my hope.

My theory is that it's like a broken thermostat. Some feedback loop that regulates some aspect of mood or reward in my brain is overly sensitive, and any "normal" outcome in some dopamine or endorphin pathway is seen by my brain as a dangerous overload of happiness. Blocking endorphin receptors with naltrexone may reduce this sensitivity or force the thermostat to reset itself.


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