Posted by Cairo on September 29, 2005, at 21:02:39
In reply to Lilly adds suicide risk to Strattera, posted by jrbecker on September 29, 2005, at 9:36:01
Strattera definitely caused a first bout of major depression in my teen daughter, even at a relatively low dose. Weaned her off even before we had our next appointment with the pdoc and her mood improved. I guess that means caution for anything with an NRI component.
Would this suggest Chrousos' theory of high CRH/NE in some types of depression?
Cairo
> http://news.yahoo.com/s/nm/20050929/hl_nm/lilly_dc
>
> Lilly adds suicide risk to Strattera
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> Eli Lilly and Co. on Thursday said it will add strong warnings to its label for Strattera, used to treat attention-deficit/hyperactivity disorder, including the risk of suicidal thoughts among children and adolescents.
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> Strattera will now carry a "black box" warning, the strongest required by U.S. regulators.
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> Lilly said there were no suicides among children, adolescents or adults taking the medication during Strattera clinical trials, but there was one suicide attempt in a patient taking the drug.
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> The warning came after the U.S. Food and Drug Administration requested Lilly to submit an analysis of adverse event data from its Strattera clinical trials data base, which identified a small but statistically significant increased risk of suicidal thoughts among Strattera-treated children and adolescents.
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> Lilly said it is working with the FDA to finalize the product label. It also is working with regulators outside the United States.
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> Lilly backed its prior sales and earnings outlook for the year and said it expects to report full-year 2005 earnings per share of $1.90 to $1.96.
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> ADHD affects 3 to 7 percent of school-age children and manifests itself in inappropriate levels of attention, concentration, activity, distractibility and impulsivity.
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> Shares of Lilly closed at $53.47 on Wednesday on the New York Stock Exchange.
>
>
poster:Cairo
thread:560940
URL: http://www.dr-bob.org/babble/20050927/msgs/561099.html