Posted by SLS on September 26, 2005, at 9:05:19
In reply to Re: **CORTISOL**, posted by SLS on September 26, 2005, at 9:00:00
> The difference in cortisol production produced by Remeron is probably too subtle to be of any use in cases where the whole HPA axis is in overdrive.
It will be interesting to see if the chronic application of a CRF antagonist will produce the kind of long-lasting changes in HPA axis function that we are looking for. Hopefully, there won't be a tendency towards "poop-out" as the system might try to recreate a dysfunctional homeostasis. Of course, CRF receptors are located in brain regions that are not involved in HPA axis regulation. Perhaps these sites will prove important in the treatment of depression.
- Scott
poster:SLS
thread:558802
URL: http://www.dr-bob.org/babble/20050921/msgs/559750.html