Posted by yxibow on September 24, 2005, at 21:33:13
In reply to Does Wellbutrin have methamphetamine properties?, posted by ButterflyHigh on September 24, 2005, at 20:39:10
> I heard it did, and I tested positive on a drug screen for them - and I do not take any sort of them.This is rare, but I don't deny what happened to you.
> If this is true, is this necessarily a good thing guys? And if true, how in the heck does a methamphetamine - type ingredients get put into an antidepressant - but more importantly why? To give depressed persons a kinda like 'high'?
> *pondering this*
Wellbutrin is not itself directly an amphetamine, it is structurally similar to diethylproprion (Tenuate), which is a not currently in favor appetite suppresant. It is similar to cathinone (Khat), which is a ketone amphetamine and used extensively as a street drug in the near and middle east.
As for the effects, it does have stimulant properties; it is a weak inhibitor of dopamine uptake. Its metabolites are perhaps just as important, they are at least if not longer lived than the medication itself.
This is more of a medical description of it; perhaps someone can add to their personal experience. For myself, it eventually became too stimulating and caused obsessive thoughts that made my insomnia even worse. But for others, it has been shown to be effective as both an antidepresant and a smoking cessation agent.
poster:yxibow
thread:559197
URL: http://www.dr-bob.org/babble/20050921/msgs/559227.html