Posted by Racer on September 24, 2005, at 21:11:47
In reply to Re: Hypotension and propranalol » Racer, posted by Cairo on September 24, 2005, at 20:28:05
> Would pindolol be any better, in your opinion? I've been toying with asking for a beta-blocker for a long while as I've that wound up anxiety such as you described, but I have postural dizziness all the time. A tilt table test was "normal", though my lower legs turned purple. I've taken my own blood pressure in bed, getting up, etc. and sometimes it goes down instead of up upon arising. Only Cymbalta at 5mg seemed to help with the postural dizziness.
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> I read somewhere that if your BARS receptors (beta adrenergic receptor) are hypersensitive, giving an SSRI along with other medications with SSRI effects (such as trazodone)adversely impacts the BARS receptors. The researcher (I think P. Wood MD at LSU) said that using Pindolol or Inderal would help "reset" the BARS. Can't find my link to that info, though and couldn't bring it up on PubMed.
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> My Pdoc won't prescribe Inderal for me as he's worried about the BP. I want to get off Klonopin that I needed to start for panic attacks induced by Topamax. Maybe I need to talk to my Internist. She's pretty sharp and maybe would look into it for me.
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> Have you heard anything about this BARS and SSRIs?
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> Thanks.
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> Cairo
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> >I haven't read anything about it, no, but I suspect that a doctor who won't prescribe propranalol is unlikely to prescribe pindolol, either? Wouldn't you think? I have a problem with postural hypotension, but also with a sort of idiopathic hypotension -- I can be walking along, happy as a clam at high tide, and suddenly drop. Happens when I stand for any length of time, too, unless I fidget a LOT. {shrug} Idiopathic, heavy emphasis on the IDIO...
If the fact that the dose of a beta blocker used for anxiety is so much less than the dose for hypertension doesn't sway your doctor, it might be worth asking about a calcium channel blocker. Verapamil is the one I've heard most about as a mood stabilizer and anxiolytic. If propranalol hadn't worked for me, that's what I would have asked for.
Hope that helps.
poster:Racer
thread:558435
URL: http://www.dr-bob.org/babble/20050921/msgs/559212.html