Posted by pro_social_soon on September 7, 2005, at 4:18:08
Since Nicotinamide/Niacinamide is considered endogenous ligand for benzodiazepine-GABA receptors would it be wise to use it while tapering off Klonopin (1mg -> 0.5mg in 2 weeks -> 0mg in another 2 weeks) ?
"Niacinamide reduces the psychological effects of stress and anxiety. Niacinamide has been shown to be effective in alleviating anxiety, elevating the aggressive reaction
threshold, and decreasing fighting (Akhundov et.al. 1993). It may be an effective natural alternative to benzodiazepines. Niacinamide has demonstrated benzodiazepine-like actions (Mohler et.al. 1979). Niacinamide is thought to be an endogenous ligand for the benzodiazepine-GABA receptor complex. It potentiates the anticonvulsant effects of diazepam (Kryzhanovskii, Shandra 1985). Study participants report they sleep better when taking niacinamide."
poster:pro_social_soon
thread:551781
URL: http://www.dr-bob.org/babble/20050901/msgs/551781.html