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Neurogenerative properties of lithium

Posted by Squiggles on August 7, 2005, at 12:11:59

I've come across this theory that lithium
has neurogenerative and neuroprotective
properties in the brain (cells and neurons?).
There is some optimism that lithium can
therefore be used not only for bipolar illness,
but such degenerative brain diseases as
Alzheimer's, Parkinson's and others.

An example of research in this are is
Dr. Husseini Manji's work (Chief of the Laboratory of Molecular Pathophysiology at the National Institute of Mental Health), see

http://www.bpkids.org/site/
PageServer?pagename=lrn_004Dr

I have a question about this theory: if
lithium protects, even regrows neurons or
brain cells, and thus protects the brain
from derpession and bipolar depression,
how is it that upon cessation of the drug,
bipolar symptoms return? Does it have
something to do with the rate of neural
growth? As i have written here before,
I experienced severe and sucididal psychotic
bipolar symptoms after 5 months on a corrupt
or depleted or low dose of lithium preparation
and was revived on reistatement of my old strong
preparation.

Any suggestions would be appreciated.

Thank you

Squiggles


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poster:Squiggles thread:538676
URL: http://www.dr-bob.org/babble/20050803/msgs/538676.html