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Thanks for the quick response. » SLS

Posted by Jedi on August 3, 2005, at 13:05:03

In reply to Re: Question for SLS: Nortriptyline with Parnate?, posted by SLS on August 3, 2005, at 7:33:47


> I'm getting some mild relief from the following combination:

Parnate 80mg
nortriptyline 100mg
Lamictal 150mg
Abilify 10mg
Trileptal 900mg
-----------------------------------------------
Thanks Scott,

Another thought I had was augmenting the Nardil with desipramine. I believe I read in one of your posts that this should not be a problem because of the low serotonic effect of desipramine. Since Nardil is the only med that has ever worked for my severe atypical depression, maybe adding a more energizing drug to the mix would help with the side effects.

I've augmented in the past with lithium, but not while taking Nardil or Parnate. This would be a fairly easy trial, since I wouldn't have to taper off Nardil to try it.

The only newer anti-seizure medication I've used is gabapentin. I had a good response with this while augmenting several other meds. I'm fairly certain that my social anxiety is related to gaba. All of the medications that I have taken which affect gaba (phenelzine, clonazepam, & gabapentin) have helped with the social anxiety. What side effects do you get from the Trileptal?

Another option for the weight gain side effect of Nardil would be the addition of a stimulant. This would be a hard sell to my doctor, but is not without precedent. Have you had any experience with modafinil?

Thanks for any additional thoughts you may have on these augmentation stategies. I want to keep the cocktail as simple as I can, but this is not always possible with treatment resistant depression.

Jedi



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