Posted by linkadge on July 28, 2005, at 18:28:11
In reply to Re: rTMS » ravenstorm, posted by Pfinstegg on July 28, 2005, at 14:50:30
As some people know, I had built my own rTMS machiene a few years back. I havn't used it in a good 6 months.
I know this one is home made and as such is not subject to the same safety standards, but I am not so sure that rTMS is all that safe.
I will admit that it has had a positive effect on my depression when I use it, but the effect lasts only about a week.
When I stopped using it, I crashed into a extremely dark an intollerable depression, deeper than I have ever known. My vision went black on the side that I was doing the rTMS !!
And that side of my face has gone periodically numb since.
I know I bash meds, but I have to be honest when I say that I think I have done some real dammage to myself with rTMS. rTMS does increase BDNF
but its effects on neurogenesis are not as clear-cut.-------------------------------------------
Chronic psychosocial stress and concomitant repetitive transcranial magnetic stimulation: effects on stress hormone levels and adult hippocampal neurogenesis.
Czeh B, Welt T, Fischer AK, Erhardt A, Schmitt W, Muller MB, Toschi N, Fuchs E, Keck ME.
The German Primate Center, Division of Neurobiology, Gottingen, Germany.
BACKGROUND: Repetitive transcranial magnetic stimulation is increasingly used as a therapeutic tool in psychiatry and has been demonstrated to attenuate the activity of the stress hormone system. Stress-induced structural remodeling in the adult hippocampus may provide a cellular basis for understanding the impairment of neural plasticity in depressive illness. Accordingly, reversal of structural remodeling might be a desirable goal for antidepressant therapy. The present study investigated the effect of chronic psychosocial stress and concomitant repetitive transcranial magnetic stimulation treatment on stress hormone regulation and hippocampal neurogenesis. METHODS: Adult male rats were submitted to daily psychosocial stress and repetitive transcranial magnetic stimulation (20 Hz) for 18 days. Cell proliferation in the dentate gyrus was quantified by using BrdU immunohistochemistry, and both the proliferation rate of progenitors and the survival rate of BrdU-labeled cells were evaluated. To characterize the activity of the hypothalamic-pituitary-adrenocortical system, plasma corticotropin and corticosterone concentrations were measured. RESULTS: Chronic psychosocial stress resulted in a significant increase of stress hormone levels and potently suppressed the proliferation rate and survival of the newly generated hippocampal granule cells. Concomitant repetitive transcranial magnetic stimulation treatment normalized the stress-induced elevation of stress hormones; however, despite the normalized activity of the hypothalamic-pituitary-adrenocortical system, the decrement of hippocampal cell proliferation was only mildly attenuated by repetitive transcranial magnetic stimulation, while the survival rate of BrdU-labeled cells was further suppressed by the treatment. CONCLUSIONS: These results support the notion that attenuation of the hypothalamic-pituitary-adrenocortical system is an important mechanism underlying the clinically observed antidepressant effect of repetitive transcranial magnetic stimulation, whereas this experimental design did not reveal beneficial effects of repetitive transcranial magnetic stimulation on adult hippocampal neurogenesis.----------------------------------------------
I think that it can be usefull I certainly had a very robust responce to it, but I am not positive that its effects on the brain are all that benign.
When I stop using it, I have NO exectutive function at all.
Linkadge
poster:linkadge
thread:533960
URL: http://www.dr-bob.org/babble/20050728/msgs/534956.html