Posted by johnb11 on July 22, 2005, at 17:27:40
In reply to Re: High-Dose Deprenyl for Social pHobia, posted by Declan on July 22, 2005, at 15:50:31
I initially started treatment with Nardil and Klonopin. While I've stayed on Klonopin, I've had numerous changes in the drung Klonopin is supposed to be augmenting. Initial Nardil of 60 mg/day was great at first, until I realized that I had gained 10 lbs and had lost sexual function and libido. Switched to Parnate which, I believe, was 40 mg/day. Had to be careful titrating up to the final dose, as Parnate is quite activating. Parnate provided some relief - maybe 30 to 40% of what I got from Nardil. It also made me lose weight, which was a nice side effect. Undesirable side effects were dry mouth and a slowed pattern of speech. My rapid fire method of talking dropped several notches. Dropped my sexual desire/function about 20%, which was a great improvement versus Nardil.
Ultimately, I found Parnate to be of just slight help, and was unwilling to face the dry mouth, slowed speech pattern, and slight degradation in my sexual enjoyment. Tried numerous other meds, including Citalopram, Venlafaxine, Prozac, etc. I think I tried just about every one. None seem to provide noticeable relief from SP.
I did have a 2 week trial of 60 mg/day Deprenyl, with the thought that, at the higher dose, Deprenyl loses its MAO-B selectivity, and then takes on a profile more similar to Nardil and Parnate. Should have waited for about 6 weeks to give it a fair trial. Mental clarity was greatly enhanced, and I had no trouble sleeping. One side effect was that I was constantly thinking of and wanting sex. Sort of like the porn channel being on 24 hours per day.
John
poster:johnb11
thread:531505
URL: http://www.dr-bob.org/babble/20050718/msgs/531768.html