Posted by linkadge on July 22, 2005, at 16:28:42
In reply to Re: About my post..and Suicide..., posted by linkadge on July 22, 2005, at 15:40:32
I think a lot of people could do a lot better than they think without medications.
Some studies show that EPA is as effective as standard antidepressants for some. It is being investigated now as a potential prescription product. I certainly attain some help from it.
Just because I don't rely on pharmacudicals does not undermine the degree of my illness. I think people try to use this as a way to guage other people's illness. I have been hospitalized three times, seen 7 psychiatrists, 5 doctors, 3 counsellers, and was once "convinced" that I needed 5 medications to get by. I have been on 33 different psychiatric meds over the years, and I was offered ECT at one point.
But playing the "this is how sick I am" game is dumb, because it mentally locks you into a position. If you're convinced you're sick, then sick you'll stay.
I am doing better than I was. I am not happy by any strech of the imagination, but I am doing better.
Oh and I got the information that most depressions do not last longer than a year from the book "Drugs and the Brain" by Solomon H. Snyder.
-------------------------------------------
Some interesting Abstracts
-------------------------------------------
Spatial learning and physical activity contribute to the induction of fibroblast growth factor: neural substrates for increased cognition associated with exerciseWheel running alters serotonin (5-HT) transporter, 5-HT1A, 5-HT1B, and alpha 1b-adrenergic receptor mRNA in the rat raphe nuclei.
Biol Psychiatry. 2005 Mar 1;57(5):559-68.
BACKGROUND: Altered serotonergic (5-HT) neurotransmission is implicated in the antidepressant and anxiolytic properties of physical activity. In the current study, we investigated whether physical activity alters factors involved in the regulation of central 5-HT neural activity. METHODS: In situ hybridization was used to quantify levels of 5-HT transporter (5-HTT), 5-HT(1A), 5-HT(1B), and alpha(1b)-adrenergic receptor (alpha(1b) ADR) messenger ribonucleic acids (mRNAs) in the dorsal (DRN) and median raphe (MR) nuclei of male Fischer rats after either sedentary housing or 3 days, 3 weeks, or 6 weeks of wheel running. RESULTS: Wheel running produced a rapid and lasting reduction of 5-HT(1B) mRNA in the ventral DRN. Three weeks of wheel running decreased 5-HTT mRNA in the DRN and MR and increased alpha(1b) ADR mRNA in the DRN. After 6 weeks of wheel running, 5-HTT mRNA remained reduced, but alpha(1b) ADR mRNA returned to sedentary levels. Serotonin(1A) mRNA was increased in the MR and certain DRN subregions after 6 weeks only. CONCLUSIONS: Data suggest that the central 5-HT system is sensitive to wheel running in a time-dependent manner. The observed changes in mRNA regulation in a subset of raphe nuclei might contribute to the stress resistance produced by wheel running and the antidepressant and anxiolytic effects of physical activity. [Abstract]I like the line:
"Wheel running produced a rapid and lasting reduction of 5-HT(1B) mRNA in the ventral DRN"
Linkadge
poster:linkadge
thread:530123
URL: http://www.dr-bob.org/babble/20050718/msgs/531729.html