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Re: Anyone helped by just 20mg/day of Cymbalta?

Posted by Dave001 on July 20, 2005, at 20:05:35

In reply to Re: Anyone helped by just 20mg/day of Cymbalta? » Dave001, posted by ed_uk on July 19, 2005, at 17:31:44

>> Studies wouldn't be of much use if that were the case. [... Studies
>> don't help us appreciate idiosyncrasies, but in this case they do
>> help us determine the *probability* that an individual will respond
>> to a given dose.]
>
> They are of use because they give a good indication of what dose
> would be suitable for 'most' people.

That's more or less what I said. You snipped the relevant context
(reintroduced within brackets above).

>> I'm not saying that it's not *possible* that so and so responded to
>> only 5 mg of duloxetine; I'm saying that it's not *probable*.

[...]

>> And we have no way of knowing whether it's the medication or a
>> placebo effect that is responsible for the results.
>
> True :-) We can only guess.

That's correct, and it is statistically more probable that the response
was a placebo effect (judging from the aggregate results of the
duloxetine studies). Thus the guess that it's a placebo effect seems
more plausible to me than the alternative explanation.


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poster:Dave001 thread:527897
URL: http://www.dr-bob.org/babble/20050718/msgs/530817.html