Posted by SLS on July 20, 2005, at 18:53:08
In reply to Re: About my post..and Suicide... » SLS, posted by linkadge on July 20, 2005, at 16:54:13
> In your own words.......
>
> "I think that most of our current treatments probably work by producing compensatative changes in the brain rather than producing a true cure."
>
> now how can this co-exist with
>
> "When I responded well to antidepressants, it certainly did "bust" the underlying illness, not just selected symptoms. It cured everything."
I guess *I'm* "busted".:-)
I am guilty of poor wording in an attempt to make a point. The point is, the entire syndrome resolves as one truly does achieve and experience full remission. The compensation might be as simple as changes in receptor numbers and the downstream events that produce them. Sometimes, I conceptualize antidepressant response as a resetting of the thermostatic feedback values. If you push the system one way or the other - for example 5-HT reuptake inhibition versus acceleration - the system is forced to compensate in such a way as to recreate the proper dynamics. The proper dynamics *is* the "busting" of the illness. For some people, this re-regulation remains intact, even after the antidepressant is removed. Perhaps this is the "cure".
- Scott
poster:SLS
thread:530123
URL: http://www.dr-bob.org/babble/20050718/msgs/530762.html