Posted by willyee on June 26, 2005, at 16:06:14
In reply to Re: Comment 2 question... » willyee, posted by SLS on June 26, 2005, at 15:50:51
> I am not terribly surprised that Lamictal caused you to become manic. What I am surprised at is that lithium was a necessary catalyst to precipitate the mania. What were your blood levels at the time?
>
> I wouldn't be so surprised that lithium didn't prevent a manic reaction to another drug. Lithium, at bipolar dosages, does very little to treat my mania once it is triggered. But it is quite an enigma that lithium should actually cause the mania. I guess its pro-serotonergic effects play a part in such a reaction.
>
> I am glad you find Neurontin helpful. I believe the drug is currently overlooked by psychiatrists as a reaction to two facts. First, it does not seem to make for a good mood stabilizer as monotherapy. This might make some doctors to view the drug as worthless when it might actually have utility as an adjunct to other mood-stabilizers. Second, there might be some backlash to the media pronouncement any litigation accusing the drug manufacturer promoting it for off-label uses. It seems that the pendulum has swung too far in the opposite direction. At first, it was handed out like candy. Now, it seems unusual that it be used as a mood-stabilizer or an adjunct to antidepressants. I believe that Neurontin is not just an expensive placebo. I hope more work is done to establish the spectrum of therapeutic properties that Neurontin actually possesses.
>
> With Gabitril, did you experience any irritability?
>
> What is your current diagnosis and what medications are you taking now? Are they helping?
>
> Be well.
>
>
> - Scott
Gabitril as a adjunct in VERY small doses worked fine,especialy when klonopin was in the mix,perhaps its providing acutal gaba for the benzo to work a lil more efficently.Now alone,gabaitril was a nightmare,literally i tried it alone and had awful nightmares,body termors,horrable depression,etc etc.
I remember reading gabitril simply provides the brain with gaba,not much more,where as most of the other stablizering gaba meds do much more,neurontion has effects i think it was on sodium channels,as well as NUMEROUS other effects,it doesent not simply add gaba to the brain.Neither does tegatrol,or even ghb for that matter,gabatril does and they stated it does little more.
So taking gabatril alone is usualy not done,stockpiling ur brain with gaba isnt the answer.
To answer ur question more,i had a good 2 week run with using it in very small doses with parnate.After time however i was noticing a lot of body tremor,i also wasnt getting the relief any longer,so to just get side effects and no benifit,i choose to end its run.But the relieaf it did provide at a point with parnate was great,the stimulate AD properties were enhanced,and then there was a very strong social ehnacment,and a decrease in ocd type thinking and behaviour.I remeber thinking i found the golden combo,if i had a nickel for every time i believed i found the ANSWER i ,well i could actualy pay my p doc bills!
poster:willyee
thread:519149
URL: http://www.dr-bob.org/babble/20050622/msgs/519346.html