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Neurontin has saturable bioavailability!

Posted by ben on June 26, 2005, at 1:12:13

In reply to Re: From Neurontin to Lyrica ?!, posted by ben on June 26, 2005, at 0:03:50

Gabapentin has a saturable bioavailabilty - that means if you are taking about 1600 mg/day it is nearly the same as 2400 or 3600 mg/day. I remember someone said "the problem with Neurontin is it stops working after some time". Thats perhaps the reason. Your system adapts in a way and then you cant give your system more of gabapentin. The uptake is limited = saturable. What about pregabalin? Why it is causing weight gain? It doesnt act exactly like gabapentin or not only like gabapentin. Is there any influence on the HP axis?!


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poster:ben thread:518580
URL: http://www.dr-bob.org/babble/20050622/msgs/519039.html