Posted by Shawn. T. on June 21, 2005, at 14:18:53
In reply to wellbutrin - 3rd leading cause of drug seizures ?, posted by linkadge on June 20, 2005, at 20:25:39
That only applies to 279 patients at St. Vincent's Hospital in New York. Only four patients were on bupropion, and "Sleep deprivation, previous history of attention deficit disorder and bulimia, and previous heavy alcohol use were associated in three of the patients taking bupropion who had seizures." Wellbutrin is contraindicated in patients with a current or prior diagnosis of bulimia
or anorexia nervosa because of a higher incidence of seizures noted in patients treated for bulimia with the immediate-release formulation of bupropion. It's also contraindicated for people undergoing abrupt discontinuation of alcohol use. So is it fair to judge Wellbutrin based on the article cited? I think not, especially with regards to the extended release formulations that are properly prescribed. Also, the mechanism of action of bupropion is not as elusive as the author makes it seem.Shawn
poster:Shawn. T.
thread:516244
URL: http://www.dr-bob.org/babble/20050617/msgs/516636.html