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Re: Generic vs Non Generic - Ed? SLS? Larry?

Posted by SLS on June 7, 2005, at 16:25:32

In reply to Generic vs Non Generic - Ed? SLS? Larry?, posted by Maxime on June 7, 2005, at 14:21:47

> I think we have had this discussion before. About where generic versions of a med are as good as the brand.
>
> The only reason I am bringing it up again is because when I saw the psychopharmacologist he asked me whether I had taken generic Prozac or the brand version when it pooped out on me. I asked him if it made a difference and he said that if I had been taking the brand name and then switched to the generic form it could be one of the reasons it stopped working.
>
> Has anyone come across any articles about this? What are your thoughts?


Your doctor is absolutely right.

Although this might not have been the case for you, several of my doctors have had people relapse once they switched to the generic and later recover once the name brand was restarted.

Brand names vs generics vs other generics are not always bioequivalent. Those "inert" ingredients can make all of the difference in the world in drug preparations. Apparently, even the name brand Nardil does not show equivelancy between the old preparation and the new one.

All of that being said, I think if you titrate using a generic and continue with that same brand generic, I don't see how it could make much difference. Unfortunately, pharmacies are at the mercy of their wholesalers as to which generic brand will show up on the shelves on a weekly basis. If you can make sure to use the same brand generic, I think you should be OK.

Who knows...

The FDA allows for more variation in the measurements in generics than they had in the original name brand, so...


- Scott

 

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