Posted by yesac on June 6, 2005, at 14:34:26
In reply to Re: Ascendin SLS, MedEmpowered » yesac, posted by SLS on June 6, 2005, at 5:10:56
> I never much cared for the idea of using a single medicinal preparation containing an antidepressant with a antipsychotic. I think it can make a mess of things. It would be better to titrate each independantly to optimize treatment.
You're probably right. I don't know how much I like the idea either. I certainly am not a fan of Symbyax, but that's more because they took two already existing drugs and made them into one, which seems stupid to me.> It is difficult to say whether or not Asendin will be more or less problematic with micturition (initiating urination) than desipramine was. Although both are anticholinergic, the more potent NE properties of desipramine probably amplify some of these side effects. In any event, knowing that you have a sensitivity for side effects would argue in favor of a very slow titration.
That whole problem scared me away from TCAs. But I have been on other drugs with norepinephrine reuptake and didn't have problems, so maybe I should give another TCA a chance.Honestly though, I am kind of afraid of all ADs at this point because not one of them has helped me and several have really been much worse. So I wonder if maybe I should just steer clear of them from now on. I guess you can never know how any one drug will affect you though.
> How did you go about initiating and titrating desipramine?
I can't exactly remember, it's been a while.... I think I started with 10mgs maybe and stayed on that for a week, then went up to 15, then 20.... or maybe it was up to 20mgs then 30. I was on it for a total of 3 weeks.
poster:yesac
thread:507989
URL: http://www.dr-bob.org/babble/20050606/msgs/508588.html