Posted by cache-monkey on June 1, 2005, at 17:50:39
In reply to Re: which ANTIPSYCHOTIC helps most for depression??, posted by bipolarspectrum on June 1, 2005, at 16:03:08
> Thanx for the replies,
> I like the idea of abilify, with its unique d2 agonist/antagonism... Just wondering about the study u were talking about cache... the only big study i can find involves depressive symptons in psychotics..
> bpsIt's a company-sponsored study, but led by Dr. Joe Calabrese who is a big name in bipolar med research. Most of the information on the BOLDER study can be found on a Seroquel company website:
http://www.psychiatryinpractice.com/
Click on "Seroquel News" link on the left for various press releases about the study.More informative is to click on the "Bipolar webcast Feb 05" and view the Webcast portion for Calabrese. This outlines how Seroquel stacks up agains Zyprexa on the MADRS.
Obviously this has to be taken with a grain of salt, since it's company sponsored. But Calabrese is a pretty good researcher and admits his own surprise with the positive findings of the study. But in terms of the benefits, the study seems to be well-designed and was double-blind, so it's kind of hard to argue with. In terms of the side effects, that's might be where a little spin comes in...
Best,
cache-monkey
poster:cache-monkey
thread:506074
URL: http://www.dr-bob.org/babble/20050601/msgs/506436.html