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Re: can desipramine and parnate be combined?

Posted by SLS on May 10, 2005, at 8:38:59

In reply to can desipramine and parnate be combined?, posted by iforgotmypassword on May 9, 2005, at 17:57:10

> ive been on 300mg desipramine forever, the zyprexa isnt helping, is there anything wrong with trying it out?

No.

It is considered to be a safe combination if administered properly. This combination is the only thing that ever got me well. Unfortunately, the doctor elected to discontinue it after only 9 months. When I returned to the combination after a subsequent relapse, it never worked again.

I have been on as much as Parnate 120mg + desipramine 200mg and Parnate 80mg + desipramine 300mg.

It has been suggested that it is safer for one to already have the TCA on board before adding the MAOI. To be conservative, it might be a good idea to check your blood pressure several times during the first few days to be sure it hasn't risen. Be wary of a headache during this time as it might be indicative of hypertension. This is an infrequent reaction, though. It can even happen when starting Parnate as monotherapy.

Good luck.


- Scott

 

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