Posted by Ritch on May 5, 2005, at 23:34:03
In reply to Re: Keppra - causes mania? » SLS, posted by theo on May 5, 2005, at 19:26:00
> > > I can always try Keppra again, but I know it's limitations and thought I might try Depakote first.
> >
> > What limitations?
> >
> >
> > - Scott
>
> Limitations in dosage mainly. If I go above 750mg I can get extremely impatient and angry on it, which can be fixed with a dosage adjustment down but to dose Keppra effectively, I have to take it 3 times daily which can also get old because it seems like all I'm thinking about is when to take my next dose.
>
> Keppra is hard to explain. It's good in the way that it clears your mind, but at the same time I can get hostile and weak. I work out at the gym as much as possible and although Keppra doesn't make me feel tired, it can make me extremely weak at times. I also have a hard time reading, following words on a page, which can get frustrating.
>
> If Depakote doesn't work, I will try Keppra again and just deal with the sides I guess. The only reason I quit Keppra was because my pdoc added Lamictal to help with depression and I starting getting mega side effects. I dropped the Keppra to get a true read on the Lamictal, which I eventually found was the true culprit for the side effects and dropped it. So here I sit.
>
>You seem to be experiencing some similar effects that I have and am experiencing with Keppra. There does seem to be a dose-dependent relationship (in my experience) with ability to help as a hypnotic (125mg doesn't work and actually worsens middle insomnia for me-but 250mg helps). Also, I have been getting significant relief from the anergic depressive symptoms, but with the trouble of increased grouchiness and impatience. I haven't had explosive temper episodes (which is good), but I don't feel too confident that they wouldn't happen at a higher dosage (say higher than 500mg total daily). I had the "asthenia" experience with Keppra if I took daytime doses higher than 125mg-felt like a rag doll. Good for psychomotor agiation... but the stumbly, wobbly feel is a bummer.
poster:Ritch
thread:487624
URL: http://www.dr-bob.org/babble/20050504/msgs/494314.html