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Re: On Cymbalta 4 1/2 months now » Sarah T.

Posted by SLS on April 30, 2005, at 15:11:49

In reply to Re: On Cymbalta 4 1/2 months now » SLS, posted by Sarah T. on April 30, 2005, at 14:14:43

> Hi Scott. Can you tell me more about pindolol's additional effects on serotonin function?

Pindolol blocks the 5-HT1a serotonin autoreceptors from "seeing" serotonin. These receptors are located somatodendritically. What this really boils down to is that the increase in serotonin produced by SSRIs is not allowed to signal the neurons to turn-off their production and release of serotonin.


- Scott

 

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poster:SLS thread:491584
URL: http://www.dr-bob.org/babble/20050428/msgs/491959.html