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Re: ANY STELAZINE EXERIENCES PLEASE!!!!!!!!!!!!! » ace

Posted by ed_uk on April 28, 2005, at 14:06:34

In reply to ANY STELAZINE EXERIENCES PLEASE!!!!!!!!!!!!!, posted by ace on April 27, 2005, at 23:49:45

Hi Acie!

Trifluoperazine can be a useful in the short-term treatment of severe anxiety, preferably at a dose of 1-2mg a day. Take care with the dose, if you take too much you will regret it. High doses can be extremely unpleasant. 1mg/day is a suitable starting dose.

Trifluoperazine is not generally suitable for the long-term treatment of anxiety, unless all else has failed and the anxiety is extreme. Even low doses may be substantially more likely to cause tardive dyskinesia than the atypical antipsychotics. To give you an example, after 12 months treatment with haloperidol (Haldol), which is pharmacologically very similar to trifluoperazine, 12.3% of the sample had developed tardive dyskinesia. This was despite the fact that the average dose of haloperdol was very low, only 1.68mg per day, which is approximately equivalent to 3mg/day trifluoperazine.

In the treatment of anxiety, trifluoperazine is probably best taken intermittently, either as single isolated doses or for a few days at a time. Trifluperazine is only suitable for the treatment of moderate to severe anxiety. It is important to find the minimum effective dose. I would not recommend taking it for more than a couple of weeks at a time. In addition, I think it's unlikely that you will find trifluoperazine to be a more effective anxiolytic than risperidone. In fact, you might find it less effective.

Take care,
Ed.


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