Posted by Ritch on April 12, 2005, at 10:10:31
In reply to Uridine- Phase I trial, posted by Peter S. on April 12, 2005, at 0:07:20
>...Uridine is a biological compound essential for the synthesis of DNA and RNA, the basic hereditary material found in all cells, and numerous other factors essential for cell metabolism. Uridine is synthesized by the power plant of the human cell known as the mitochondria. The rationale for uridine therapy in neuropsychiatric disorders is supported by pre-clinical and clinical research. Researchers at McLean Hospital previously demonstrated that uridine is active in a well-validated animal model of depression. Recent reports indicate that certain genes that encode for mitochondrial proteins are significantly down regulated in the brains of bipolar patients. This new insight suggests that the symptoms of bipolar disorder may be linked to dysregulation of energy metabolism of the brain.
Hey, thanks for posting that! "Dysregulation of energy metabolism of the brain"... wow, I think they may be closing in on the real trouble. Fundamentally, I would agree that it is an energy management problem, and all the symptoms stem from that....
poster:Ritch
thread:483146
URL: http://www.dr-bob.org/babble/20050408/msgs/483242.html