Posted by cache-monkey on April 7, 2005, at 0:47:16
In reply to Re: Abilify vs. Seroqueled_uk, posted by anodyne on April 6, 2005, at 21:35:52
Hey Dan,
I would consider giving diazepam a shot. I don't know how you might react to it in terms of your anxiety levels, but it's less likely to truck with your sex life than clonazepam.
There's a study fingering clonazepam as the worst benzo in the sex department. I think I posted about it in another thread which you were a part of. (I can repost the abstract again if I'm mistaken...)
Anyway, I was having sexual problems on clonazepam as well. I switched to diazepam and, voila, problem solved. I also found the diazepam a little better in terms of its anxiolysis-to-sedation ratio.
Another thing re: the Seroquel. Granted it's company-sponsored, but there's a recent double-blind placebo controlled study done on it. (Decent sample size, too -- N>500.) They found not only benefits for depression, but also for anxiety and sleep. Both of these are new findings, since it has only been approved for the treatment of mania so far.
Here's a link to a summary of the Seroquel study:
http://www.pslgroup.com/dg/24415a.htmGood luck, and let us know what happens if you decide to try the Seroquel.
Best,
cache-monkey> Hey Ed, good to hear from you.
>
> > What side effects do you have from clonazepam? Have you tried any other benzos?
> >
>
> I have been taking varing doses of Clonazepam from 2mg a day to .5mg a day for about 18 months. I must say it WORKS and tolerance has not been an issue. Howver it has killed my libido, caused some other sexual SE and caused me to be a bit lethargic (probably all symptoms of the same thing). Also, I get this low level of depression when I take it every day for a couple of months.
>
> I have tried ativan (artificial feel), xanax (good night), xanax xr (drowsy & limited effect) so far. Thought about giving diazapam a try but I'm not sure it will be any better than the clonazepam.
>
> Benzos certainly come closest to making me feel "normal" and boost everthing from concentration, motivation, socialability - all at the expense of my physical energy level and sex life.
>
> I thought about augmenting clonazepam with something like Provigil, but anything activating doesn't seem to agree with me. And my Pdoc is hesitant in precibing one med to conteract the SE of another.
>
> Any thoughts on the Provigil?
>
> It seems like a anticonvulsant might be the way to go. Perhaps it will enable me to cut down on the clonazepam. I thought Seroquel might do the same but I hated Abilify.
>
> Sorry for the ramble. -Dan
>
poster:cache-monkey
thread:480813
URL: http://www.dr-bob.org/babble/20050404/msgs/480984.html