Posted by barbaracat on March 26, 2005, at 21:12:18
In reply to I can believe it, posted by linkadge on March 26, 2005, at 20:15:13
Yeah, try to find that article, Linkadge. I remember hearing something about it a while back - maybe from you, but it caught my eye. My question is, is the increase in BDNF sustained?
I too have a funny feeling that high doses cause getting hooked and damaged and drug companies know exactly what they're doing. I was on 300mg zoloft for 2 years. Could practically smell the synapses frying. Gives me great comfort that brain cells regenerate. One of the reasons I'm a lithium fan is for it's neuroregenerative benefits.
BTW, just heard that the kid on the Indian reservation who shot all those people had his Prozac increased the week before. Just like Columbine, just like Springfield, the kids were either on SSRIs or stopped them abruptly. - Barbara
> I read a few studies which showed that in a few circumstances, an A.D. will raise BDNF at a "subtheraputic dose" and actually decrease it at more "theraputic doses". I will try to find the study. It was done on rats with amitryptaline. The same is true for exercise. Exercising a certain amount will increase BDNF, but futher exercise can actually deccrease it.
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> I think that the drug companies push for higher doses than what was shown in animal models to help depression because they want to get you hooked on them forever.
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poster:barbaracat
thread:475145
URL: http://www.dr-bob.org/babble/20050326/msgs/476026.html