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Re: Klonopin (clonazepam) - sexual disfunction » sdb

Posted by cache-monkey on March 20, 2005, at 16:41:04

In reply to Klonopin (clonazepam) - sexual disfunction, posted by sdb on March 20, 2005, at 13:05:39

I noticed a marked decrease in libido and erectile function on Klonopin, but only after being on it for a little while. I've reduced my dose (from 1.5 mg to 1.0 mg per day) and it's gotten much better.

I don't know if, after a while at the higher dose, the problems would further diminish, but among the benzos Klonopin seems to be a particularly egregious offender in the sexual domain: see the abstract below.

I'm actually going to switch to Xanax XR, as I never experienced any difficulties when using the short-acting version...

Hope this helps somewhat.

Best,
cache-monkey

================================
Fossey MD, Hamner MB. "Clonazepam-related sexual dysfunction in male veterans with PTSD." Anxiety, 1994-95, 1(5):233-6.

Abstract
Medication-induced sexual dysfunction can significantly interfere with patients' quality of life and lead to poor compliance. This retrospective study examined the records of 100 male veterans with post-traumatic stress disorder (PTSD) selected in alphabetical order from an active treatment file of 230 patients. Forty-two patients had received clonazepam (mean maximum dose: 3.4 +/- 1.6 mg/day) at some point during their treatment. Of these, 18 (42.9%) complained of significant sexual dysfunction (primarily erectile dysfunction). Eighty-four patients received diazepam (mean maximum dose: 52.1 +/- 29.7 mg/day), nine received alprazolam (mean maximum dose: 5.2 +/- 2.8 mg/day) and eight received lorazepam (mean maximum dose: 3.8 +/- 2.4 mg/day). None of these patients complained of sexual dysfunction during treatment with these three other benzodiazepines. Our findings suggest that benzodiazepines, particularly clonazepam in the current study, can be a cause of sexual dysfunction in many male patients. Prospective studies comparing the overall clinical utility of various benzodiazepines are indicated in this and other clinic populations.
================================


> I have never used Klonopin for longterm. But during stressfull weeks this drug is really helpfull. But I have a loss of libido and difficulty to have erectjon with Klonopin.
>
> Would this bad sideeffect go away with time, if I would take it regularely? Do you also have this problems is it common?- Or does somebody have good results with comedication for example trazodone, buspirone, wellbutrin and perhaps mirtazapine? I have myself good results with trazodone alone in libido but it does delay ejaculation and it does not help with bp and sp. Buspirone alone does nothing for libido and it does nothing for bp and sp.


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