Posted by Larry Hoover on March 14, 2005, at 11:31:23
In reply to Percodan/Percoset Experiences??, posted by cubbybear on March 14, 2005, at 5:03:24
> I'd like to hear from anyone who took either of the above analgesics (oxycodone) for short or long term use. Do you think it's as addicting as the websites say it is? Why did you use it? Any problematic discontinuation or side-effects?
>
> thanks muchI regret to acknowledge that I have had some lengthy interactions with Percocet. Not because of the drug, but because of the necessity for it. Pain. Chronic pain sucks.
I've never had discontinuation problems, and I believe it's because of how I use it.
In general, the receptors with the most affinity for oxycodone are those responsible for the pain sensation itself (called nociceptors). The analgesic effect comes from the blocking of nociceptors by oxycodone. Other receptors also have affinity for oxycodone, and those are responsible for the psychoactive effects, and any subsequent problems with addiction.
I take great pains (sorry for the pun) to titrate the dose according to my degree of discomfort. I try to play off a balancing act between discomfort and "getting a buzz". If the dose I have chosen gives me a buzz, then I took too much. If the dose I took has not made me more comfortable after one hour, I took too little. I break pills, and intuit the dose I expect to need. I've gotten pretty good at guessing how much to take.
Also, by breaking pills, I can maintain a more stable blood concentration. Taking a half tablet every two hours is the same total dose as one tablet every four hours, but the blood concentration does not oscillate as much.
I never seek to be pain free. The pain free dose (for me) is also a psychoactive dose. The pain-controlled dose is not psychoactive.
I also augment the anti-inflammatory aspect. Percocet is oxycodone with acetominophen. Percodan is oxycodone with aspirin. I find that Percocet with Toradol (keterolac tromethamine) is a very effective combination. As is Percocet with turmeric (which contains a very potent COX inhibitor).
I have used (and am using) Percocet daily for months with virtually no side effects, and zero withdrawal effects.
Lar
poster:Larry Hoover
thread:470781
URL: http://www.dr-bob.org/babble/20050312/msgs/470848.html