Posted by chess on March 4, 2005, at 7:13:33
In reply to Re: why is LSD hallucinagenic and SSRIs are not?, posted by TheOutsider on March 4, 2005, at 5:35:07
I found this quote on the web, does it mean that LSD is hallucinagenic because it has more of an intense effect on serotonin receptors than SSRIs do? ... "Modern psychiatry uses drugs affecting the same brain systems as psychedelics, which became notorious as "recreational drugs" in the 1960s. Antidepressants in the selective serotonin-reuptake-inhibitor (SSRI) class (e.g., Prozac®, Paxil®, Celexa®) extend the effects of serotonin, a brain chemical involved in the modulation of depression, euphoria, and appetite. Hallucinogens also interact with serotonin, but as serotonin agonists they work differently than SSRI's by acting on neurotransmitter receptors in a similar manner but more so 'effectively', pushing the serotonin system into overdrive", according to Dr. Nichols, professor of pharmacology and medicinal chemistry, Purdue University."
> > LSD increases serotonin by making more of it.. SSRI'S increase serotonin by blocking the reuptake.. there's the key difference I think.. some thing when it comes to MDMA
>
> I Don't mean to be rude Mike but I think LSD works by acting as an Agonist and Antagonist at Seratonin receptors, rather than by facilitating Seratonin transmition as MDMA does...
poster:chess
thread:466257
URL: http://www.dr-bob.org/babble/20050304/msgs/466357.html