Posted by ed_uk on February 13, 2005, at 11:09:38
In reply to Re: What Ever Happened To Valium?, posted by Kon on February 13, 2005, at 10:49:04
Hi,
>most of the studies suggested somewhat greater efficacy
In many cases, the alleged superiority of high-potency benzodiazepines was probably just an artefact of the fact that non-equivalent doses were used.
For example....
>Eighteen inpatients suffering from a severe anxiety received in double-blind and crossover conditions iv and im injections of 10 mg diazepam, 5 mg lorazepam or saline t.i.d. during 5 days.
>The results demonstrate the superiority of lorazepam over diazepam on psychic anxiety, somatic anxiety, sleep and blood pressure, the only significant side-effect being drowsiness5mg lorazepam is a much higher dose than 10mg diazepam.
Regards,
Ed.
poster:ed_uk
thread:456080
URL: http://www.dr-bob.org/babble/20050212/msgs/457131.html