Posted by ravenstorm on February 7, 2005, at 20:43:18
Before I even ask my questions I have to thank Scott (SLS) for his wonderful chart on psychiatric meds. Without that, I wouldn't even be able to ask these questions, or attempt to draw comparisons (however, futile my queries may end up being!).
OK.
First, what is the difference between an
NE-alpha1 antagonist and an NE-alpha2 antagonist?Second, if I am irritable, angry and anxious on remeron, which works as an NE-alpha2 antagonist, would I also, in theory, find buspar (which also works as an NE-alpha2 antagonist) to cause the same side effects?
What about drugs that are NE-alpha1 antagonists? Serzone falls into this category, and I was never angry or anxious on serzone (BUT I was still on 5mg paxil--trying to wean off--so perhaps that made the difference?) I was also barely awake the whole time I was on it (again, I sometimes wonder if an interplay between paxil and serzone might have also heightened the drowsiness affect). I see that seroquel is also an NE-alpha1 antagonist. At a low dose would that make me irritable or not? (Since serzone didn't)
Is risperdal an NE-alpha1 or 2 antagonist? (Scott's chart doesnt specify)
Just wondering. Or is it basically just a total flip of the coin? (ie an NE-alpha 1 antagonist in one drug might affect me totally differently than that of another drug)
Any broad information about the two types of alpha antagonists (and which kind risperdal works on) would be greatly appreciated. Or if you have personal experience with the two types and how they affect you, feel free to chime in.
Thanks.
poster:ravenstorm
thread:454677
URL: http://www.dr-bob.org/babble/20050207/msgs/454677.html