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Re: Seroquel warning ?!

Posted by med_empowered on February 3, 2005, at 9:07:11

In reply to Seroquel warning ?!, posted by banga on February 3, 2005, at 8:07:57

hi! The "black box" I believe is the FDA's strongest warning measure...its something that can be done just short of resheduling a drug or ordering it off the market. Anyway, the antidepressants are now supposed to be "black boxed" with suicide warnings (tricyclics have been for years; the ssris now have to follow). It makes sense that seroquel would be black boxed...in MAD IN AMERICA, the author cites a number of letters, obtained through the Freedom of Information Act, that the FDA sent to the makers of the atypical antipsychotics (including the seroquel people). Anyway, even though the FDA did approve seroquel, there were found to be serious flaws with the seroquel studies (and the zyprexa studies, and the risperdal studies), and therefore any claim of superiority over conventional antipsychotics is highly suspect.


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