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Try Wellbutrin + Pregabalin or Gabitril or Benzo

Posted by 3 Beer Effect on January 27, 2005, at 22:26:30

In reply to Periactin and Prozac, posted by sabre on January 26, 2005, at 15:24:31

I think you would be better off by taking Wellbutrin since it has minimal effects serotonin & works mainly as some type of neuromodulator with slight Dopamine Reuputake activity which in combination boosts both Norepinephrine & Dopamine.

For the GABA you could try one of the new GABA meds like Pregabalin or Gabitril or a Benzo with little serotogenic activity (I think Klonopin & Xanax? have serotogenic activity so avoid those & take ativan or something like that).

The ADD med Ritalin boosts Dopamine Reuputake Inhibition & also boosts Norepinephrine but it doesn't last very long, & add meds by themselves without an antidepressant eventually cause a depression. You might be able to combine it with Wellbutrin although Wellbutrin seems to eliminate the pleasure inducing effects of ADD meds, i'm not sure why- perhaps its anti-smoking/craving activity limits stimulant euphoria or it may inhibit dopamine release by ADD meds. Adderall also boosts Dopamine & NE release but may also release small amounts of Serotonin as well.

Selegeline at 10 mg a day or less boosts Dopamine & Norepinephrine (its metabolites the l-amphetamines induce norpepinephrine release).


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