Posted by jparsell82` on December 28, 2004, at 0:12:52
In reply to Re: Its all about the frontal cortex, posted by bark2323 on December 26, 2004, at 11:00:23
> I think some of them do not block to a significant extent the D1 receptor (olanzapine I beleive does not, but you get a different affinity everywhere you look so who knows), and the D1 receptor is the most abundant in the frontal cortex. Anyways, are you considering adding remeron because the celexa isnt working too well, or for sleep, or some other reason? I seem to remember reading you are still not where you want to be (happy), but Im not sure, although I suppose if you were feeling good again you probably wouldnt be adding meds in the first place. Are you still on lithium, and if so what is it doing for you? I think I remember you saying it made you less depressed, or at least less suicidal, but that it made the world pretty "grey". (sorry I read this board a lot, but sporadically, and I dont post much if youre wondering who the hell this guy is)
> mattYeah, but if you have Social Anxiety Problems olanzapine blocks D2 and people with social anxiety already have low binding potential for the D2 receptor. Like you said there's Remeron... but it effects Histamine which I couldn't stand... the 5ht3-antagonist properties were welcome though as they help get rid of nausea. What about Mianserin??
poster:jparsell82`
thread:433326
URL: http://www.dr-bob.org/babble/20041223/msgs/434880.html